Sunday, July 14, 2024

Diabetic Foot Ulcers: Causes, Symptoms, Treatment, & Prevention

 Diabetic foot ulcers, often known as diabetes on feet, are a common complication of diabetes.


Diabetic foot ulcers are lesions or injuries that develop on the feet of people who have diabetes. They arise as a result of a convergence of variables, such as nerve injury (neuropathy), inadequate blood flow, and heightened vulnerability to infection.

Risk factors for developing diabetic foot ulcers include elevated blood glucose levels, prolonged duration of diabetes, smoking, hypertension, elevated cholesterol levels, and a history of prior foot ulcers.
Manifestations: Manifestations may include erythema, edema, increased temperature, discomfort, exudate, and malodorous scent in the vicinity of the ulcer.
Consequences: If not treated, diabetic foot ulcers can result in severe complications such as infections, gangrene (tissue death), and the need for amputation.
Therapy: The therapy primarily aims to regulate blood glucose levels, eliminate necrotic tissue from the ulcer, facilitate wound recovery, and prevent infection. Possible treatment modalities including wound dressings, administration of antibiotics, debridement to eliminate necrotic tissue, and offloading techniques to alleviate pressure on the foot.
References:

The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) provides information about avoiding foot issues related to diabetes. You may find more details at their website: https://www.niddk.nih.gov/health-information/diabetes/overview/preventing-problems/foot-problems
12. Medications for Weight Loss in Diabetes:

Multiple drugs have received approval for promoting weight reduction in individuals diagnosed with type 2 diabetes. These drugs function through many methods, including appetite suppression, enhanced satiety, or alteration of sugar metabolism.

Frequently prescribed medications:


Glucagon-like peptide-1 (GLP-1) receptor agonists are drugs that imitate the function of a hormone involved in the control of blood sugar levels and hunger. Some examples of these medications include liraglutide, which is sold under the brand names Saxenda and Victoza, and semaglutide, which is sold under the brand names Ozempic and Wegovy.
Sodium-glucose cotransporter 2 (SGLT2) inhibitors: These drugs function by increasing the quantity of glucose eliminated through urine. Empagliflozin (Jardiance), a kind of SGLT2 inhibitor, has demonstrated the ability to facilitate weight reduction.
Additional drugs, such as metformin and pramlintide, may also lead to slight weight reduction in certain individuals.
Factors to take into account: It is crucial to engage in a conversation with a healthcare expert on the possible advantages and drawbacks of weight loss medicines in order to ascertain their suitability for you.

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